The British Navy in Port Said is making plans for naval manoeuvres with the French fleet. Plans are delayed because the British Secret Service has been warned of possible sabotage. On a ship docking in Port Said is Madame Delacour, wife of the French naval admiral.
French financier Paul Reynard (Rathbone) is sentenced to a ten-year term in a South American penal colony for bank fraud. His wife Irene (Gurie) and Paul's faithful servant Dirk (McLaglen) travel to Rio de Janeiro to arrange for Paul's escape. But once she's landed in the Brazilian capital, Irene falls in love with American engineer Bill Gregory (Cummings).
The promotional film begins with framing device, wherein Scorsese, playing himself, describing how he discovered three and a half pages of an unproduced Alfred Hitchcock film, "The Key to Reserva". As part of this film preservation work he plans to film the script as Hitchcock would have filmed it. The film, which contains no dialogue, shows Roger Thornberry arriving at a box seat during an orchestra performance.
Having been sent a picture of her husband, a war hero reported missing in action in France, Meg Elgin, now engaged to Geoffrey Leavitt, is led to believe he is still alive and arranges a meeting at a London railway station. When she arrives there with the police accompanying her, she catches sight of a man in the distance wearing an old coat of her husband's. When he is pursued and captured, he turns out to be Duds Morrison, a former soldier and out-of-work actor recently let out of prison.
Mobster Jack Martin is hiding from the law in a small town, and he is running out of money. So he robs a bank and gets away with some loot. However, not only are the cops now after him, but so is the local mob boss Earl Dawson, who is jealous that an outsider pulled a job in his territory, especially without giving him a piece of the pie.
Steve Morgan (Tierney) is a charming sociopath who has just robbed and killed a cinema cashier. Seeking to escape, he hitches a ride to Los Angeles with unsuspecting Jimmy 'Fergie' Ferguson (North). Part way the pair stops at a gas station and picks up two women.
Police lieutenant Nick Ferrone explains the work of bail bondsmen. One such man is Vince Kane, a former police detective who worked with Ferrone. When one of his customers, Claude Brackett, is murdered, Kane investigates, not only because of his curiosity as a former cop; he has also fallen in love with Brackett's widow Lucy, an old flame.
With help from Elaine, his girlfriend, young John Dillinger breaks into her father's safe. They are caught, but Dillinger takes the rap by himself. In prison, he meets Pretty Boy Floyd and Baby Face Nelson, who join Dillinger's gang after he masterminds a prison break.
The rookie Petrosino convinces the Police Commissioner of New York City to allow him to form a special squad to combat The Black Hand on its own grounds, as success depends on the ability to speak Italian and to convince the ordinary citizens of the tenements that gangsters are not heroes to worship. Petrosino's initial opponent is Lupo Miano, a leading extorntionist. But he soon suspects it runs deeper than Lupo's obvious rackets.
A physician's death orphans his two adolescent daughters. Their older brother is able to convert some of the doctor's small estate to cash. It is late in the day, and with the banks closed he stores the money in his father's household safe.
Matt, a 19-year-old swimming coach at a country club, who is a virgin, has an affair with Vivian, a married mother in her forties whose daughter is taking classes with him. When her husband Justin finds out about the affair after finding the couple's love letters, Vivian is forced to end it, upsetting Matt. This results in a chain of reactions from photocopying of love letters leading up to Matt shooting her dead.
At the West Hills Golf Club in Westchester, E.J. Kimball (Walter Kingsford) and his son Manuel (Russell Hardie) are welcomed into the party of elderly Professor Barstow (Boyd Irwin Sr.) and his prospective son-in-law Claude Roberts (Victor Jory). Barstow sends his caddy back to the clubhouse to fetch his visor, and finds himself without his clubs when it is his turn to tee off.
Late one night, Charlie Chan is shot at a San Francisco bus station. While on a missing-persons case, he investigates a series of sensational slayings—publicized as "the torso murders," in which only the victim's torso remains at the crime scene. Chan is assisted officially by detective Jeff Hay and police captain Allen, and unofficially by his Number Two Son Jimmy and chauffeur Birmingham Brown.
Ray Eames (Arliss Howard) has spent seven years on death row for the shooting of policeman Jackie McGrath in a drug bust gone wrong. His electrocution being finally scheduled, Eames' last request is for someone to photograph his death. Paul Marish (Roy Scheider) reluctantly takes the job.
L.A. Detective Sam Dietz (Leo Rossi), struggling to emotionally survive his previous big case (the first Relentless film) is unwillingly paired with a shady FBI agent Kyle Valsone (Ray Sharkey), during a case tracking another serial killer (Miles O'Keeffe), who kills seemingly at random. But every time Dietz gets a lead, Valsone gets in the way and somewhat throws off the investigation.
T.M. Pryor, a former cop, escapes from a prison in Louisiana where he is currently serving out a sentence for killing his wife's lover. Despite the fact that his parole hearing is only two weeks away Pryor is desperate to be at his son's hospital bedside.
On a short flight to Catalina Island off the California coast, Roswell T. Forrest gets sick. When he is found dead upon landing, it appears to be murder to fellow passenger Hildegarde Withers, but she has a tough time convincing local police chief Britt and coroner Dr.
As Nick Harbin prepares for his release from prison after serving five years for a payroll heist, he refuses to disclose the location of the $260,000 he stole with two accomplices, who are now dead. Upon release, Nick is immediately confronted by reporters, police, and his ex-girlfriend Sue, who appears eager to rekindle their relationship. Sue and Nick drive to his old house, followed closely by the police, where they encounter Dave, another old acquaintance.
Ex-OSS operative Larry Brennan returns to Czechoslovakia after retiring from his military service during World War II. He is intent on seeking out a hidden cache of Nazi jewels stashed in this country during the war. There he has to join with Hedi von Hartmann, his former lover and a daughter of the German general who previously owned the gems, but Larry is not sure whether he can trust her.
After his girlfriend leaves him, lonely horror movie buff Adam Waltz moves to Los Angeles to be closer to her. There he lands a walk-on role in studio chief Connor Pritchett's latest cinematic schlockfest, Pirate Wench. One night, a killer starts stalking the set, and before long bodies are piling up.
Nightclub singer Ilona Vance is accused of murder because she was the last person to see crooked attorney Frank Hobart alive. Lt. Hargis attempts to prove her innocence.