On the back streets of Chicago, two would-be car thieves walk past a jet black car (a fourth generation Chevrolet Nova), only to turn back a few seconds later to find a red sports car (a Chevrolet Corvette Z06). As they climb inside they discover the ignition, the handles and every means of escape have instantly vanished, the windows go black around them and their screams are soon cut off. Driving out to the main street, the black car is demolished by a car flying down the road.
A decade ago, an orphanage has been rebuilt after being burned down following accusations of child molestation and abuse from the building's custodian. A group of medical students are brought in by a pediatrician-turned-doctor to rebuild the building as a foster home, while a psychotic masked assailant stalks them.
Property developers looking for the ideal South Pacific location for the new Paradise Carlton hotel, discover instead an island populated by carnivorous plants and zombies.
Just as the local grocery store is about to close, a group of six armed, masked people enter the building. They take the staff and remaining customers hostage and immediately shoot down one of the employees. One of the masked men named Spooky is then told to check whether "he" is among the hostages.
Marie Pettis has recently divorced her politician husband Greg, who was involved in a widely-publicized political scandal in New York City. To decompress, she leaves for a weekend trip in upstate New York with her new stockbroker boyfriend Robert, her sister Shirley, and their openly gay friend Nicky. They arrive to the country late in the evening, and stop in a small town.
In an atomic-powered laboratory beneath the mansion of the elderly, unpleasant, and very rich Mrs. Hettie March, Dr. Otto Frank is experimenting with brain transplantation.
Johnny Wentworth wakes and prepares to go to his job at the Dandy Donuts donut shop, where he works with his childhood friend Michelle Kester. He first retrieves his tablet from his Uncle Luther, a mad scientist who has unwittingly created a serum to reanimate the dead. While at the shop, Johnny is confronted by his girlfriend Veronica and friend Bobby, who require money.
Father Rosetti is sent by the Vatican to the small fictional city of Briscayne Falls in Pennsylvania to investigate a report of an impending virgin birth, but he is attacked on the road by mysterious bikers, making him crash and leaving him catatonic. In his place, Vatican sends Father Justin O'Carroll, not without warning him that seventy years before, the Virgin Mary appeared in an Italian village and left a message concerning the birth of a divine child at the end of the century. After arriving in the city, O'Carroll meets a pregnant, poverty-stricken 15-year-old teen, Margaret Gallagher, who is bullied by her classmates for her claims…
A middle-aged couple are hiking through the remote wilderness in the Sierra Nevada, when the wife becomes convinced someone is following them. Shortly after, an unseen assailant attacks the husband with a hunting knife, stabbing him to death. The killer then pursues his wife, and slits her throat.
When 16-year-old Loren and her family greet a new neighbor, Jared, a good-looking single guy and his dog, she senses something mysterious and dangerous about him. Her suspicions become further aroused when some of the locals begin disappearing one by one. As Loren becomes obsessed with her neighbor's behavior, she is unaware that he is monitoring her just as closely as a hungry wolf stalking its prey at night.
Writer Hilary Thomas is being pursued by psychopath Bruno Clavel, a man she once interviewed at his family's Massachusetts orchard while researching for a book. Clavel plays a cat-and-mouse game with Hilary, repeatedly breaking into her Manhattan apartment and tormenting her, often calling her "Catherine." Detective Tony Clemenza oversees the case, while Hilary struggles to find an explanation for why Clavel is targeting her. During one of the break-ins, Clavel is fatally injured, and found dead several blocks from Hilary's apartment.
In 1981, Daniel Grayham, a man with paranoid schizophrenia, escapes from a mental asylum after killing a doctor and stealing his uniform. Three years later, a sociology teacher at St. Trinian's College is murdered whilst working alone in a classroom, and a new teacher, Julie Parker, is hired by the school's handicapped priest headmaster Father Janson to take her place the following semester.
A group of friends are marooned on an uncharted island after their sailboat crashes. They quickly become aware they are not alone, as they find themselves being killed off by a group of ancient humanoid creatures resembling humans and baboons. Liz, the sole survivor after having been captured, flees and is covered in multiple plants' sap as she barrels through the jungle, so when cornered by the Alpha of the pack she realizes the creatures are blind, hunting by smell and sound, which allows her to elude him by standing perfectly still while the plant sap obscures her scent.
On a deserted beach, four boys, Miki, John, Ben and Allan, are told by an Indian the story of the monstrous marine being Wakan and seal a blood pact, a bond of their friendship and mutual assistance in case of danger. Ten years later, the boys reunite as young men and decide to go on a holiday together. But a killer shark ruins their plans.
A mad scientist named Dr. Viktor Vasilienko (Andrew Divoff) is disillusioned with capitalist society and creates a virus that is designed to make people rage with anger. In his hidden laboratory in the woods, he begins testing the virus on innocents.
Harlan Thompson (David McCallum) is the head of the biology department at Southwestern University, a small school located in an isolated southern California town. Though he dresses casually and socializes with the students, he is frequently at odds with his fellow professors and the administrators, viewing them as shallow, elitist snobs who are more interested in status than education. However, he takes a semi-liking to a young and newly hired biology professor, Michael Fitzgerald (George Wyner), and tries to stop him from being sucked into the system.
Ivan Moser (Lyle Alzado) is a serial killer who has been convicted of the rape, torture, and murder of 23 people. Moser is given the death penalty by electrocution. At his execution, he boasts of having killed 24 people.
Steve, Larry, and Rip are part of a paintball team known as "The Zero Boys". Fresh from a tournament win, the trio and their girlfriends take a leisure trip into the mountains, they stumble upon a gruesome massacre. Blood-chilling screams lead the group to a deserted cabin, where they gradually discover the horrors of the killings and the evil causing it.
The story opens with Elmira Johnson, an elderly woman who uses a Ouija board to communicate with spirits. One spirit becomes angry, manifesting as a cymbal-banging monkey toy. The toy's eyes glow red, and its cymbals cause lightning to strike Elmira's house, killing her.
While dealing with her own mental issues, Roslyn takes the night shift at a recently closed hospital's psych ward. As she experiences possibly supernatural phenomena, she comes to suspect that her husband, Cole, is a serial killer active in the area.
In 1902 Cairo Egypt, as a riot breaks out in the street, Captain Storm is assigned with a small contingent consisting of himself, Gromley, and Smolet to retrieve the members of an unsanctioned archeological expedition in the Valley of the Kings who are seeking the lost tomb of Rahateb. Storm's mission is compounded to escort the expedition leader's wife Sylvia Quentin as they take a planned route, the group encountering a strange woman named Simira whose brother Numar is helping the Rahateb expedition. Though Storm turns down Simira's offer to lead them on a more direct route, he relents after Sylvia is stung by a scorpion.
Haughty anthropology professor Harry Ballard (Karl Urban) receives a sinister videotape showing a cult called the Black Lodge ranting about a demonic plot. As it turns out, Harry's brother, Richard, killed himself a few months earlier under mysterious circumstances, possibly related to this cult; in any event, the loss has been preying on Harry's mind, sending his relationship with his girlfriend (Sally Stockwell) into a tailspin. Meanwhile, a seemingly schizophrenic young woman named Benny (Katie Wolfe), who has a penchant for lighting sparklers in alleyways for no good reason, follows Harry around and snatches him from the jaws of doom…
Jessie Holden is invited by her boyfriend, Kevin, and two friends, Freddy and Marie, to spend one Halloween night at Santa Mira Hospital, abandoned years ago due to a fire. Their friend, Emmett, is preparing the props to scare Jessie when he and his dog, Dutchess, are attacked by a ghost. Meanwhile, Allan is searching for his sister, Meg, who went missing with her friend, Caitlin, in the hospital a few days ago.
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While making popcorn, Kenny is called by an unknown person, who flirts with him. The conversation turns disturbing, and ends when a man wearing a hood and face paint breaks into Kenny's house, and rapes him. The next day, Kenny's friends discuss what happened to him, revealing that he was so traumatized from being raped that he has suffered a mental breakdown.